July 2024-

Alex, Isobel, Mackenzie and John attended the 2024 FASEB Phospholipids meeting in St.Paul Minnesota. John was a co-organizer. Alex gave a short talk, Isobel gave a flash talk, and all three trainees presented a poster. Alex received a "Best Short Talk" award and Isobel received a "Best Poster" award - Congrats!

 

May 2024 -

Damilola and Stefania have joined the lab as summer students before starting their Honours projects in September! Welcome back!

 

April 2024 - 

Isobel passed her candidacy exam and is now a PhD candidate! Congrats Isobel!

Sushant, Hunter, and John attended the 2024 HDX conference in Monterey California. Sushant gave a talk and Hunter presented a poster!

Alex has been awarded a CIHR CGS-D scholarship and Isobel has been awarded an NSERC CGS-D scholarship! Congratulations to you both!

​

December 2023 - 

Alex passed her comprehensive exam and is now a PhD candidate!

​

September 2023 - 

Mackenzie decided to stick around and start as a Masters student! 

​

June 2023 - 

Hunter has joined the lab as a mass spec technician, welcome!

​

-May 2023 - 

Alex won best poster at the Biochemistry and Molecular Biology Graduate Student Symposium at UBC, nice work Alex!

Damilola and Sol have joined the lab as summer students. Welcome! 

John was accepted to medical school at UBC, and Matt was accepted at Yale for his PhD. Well done both! 

​

-April 2023 - 

Sushant has passed his candidacy exam and is now a PhD candidate!! 

​

- March 2023 - 

Alex gave a talk at ASBMB in Seattle. 

Mackenzie and John presented their work at Honours Fest, and Mackenzie won top prize! Amazing!

​

-December 2022 - 

Harish successfully defended his Masters thesis 

​

- September 2022 - 

Isobel B has joined the lab as a Masters student, welcome Isobel! 

 

- August 2022 - 

Matthew T has left the lab to pursue a PhD at UBC under the supervision of Natalie Strynadka, and Alex has left for UBC to begin her PhD under the joint supervision of Calvin Yip and John Burke. Good luck to you both! 

 

- May 2022 - 

Mackenzie S and John E have joined the lab as Co-op students, and will both begin their honours in September. Glad to have you both!

​

- March 2022 - 

Matthew T won 1st place in Honours Fest. Congrats Matt! 

​

- November 2021 - 

​

​

​

​

​

 

 

 

 

 

 

 

 

 

 

John was inducted into the Royal Society of Canada College of New Scholars

​

- September 2021 - 

​

Matthew T has joined the lab as an honours student and Stephanie has joined as a Volunteer. Welcome! 

​

Noah has successfully defended his MSc thesis "Understanding the molecular basis of Rab-GEF activity and specificity of the mammalian TRAPP complexes'. Congrats Noah! 

 

​

- August 2021 - 

​

After several delays due to Covid, Sushant has joined the lab from India as PhD student. We are happy to have you here!

​

Manoj has succesfully defended his PhD thesis "“Molecular basis for the regulation of phosphoinositide 3-kinase 𝛄 (PI3K𝛄)" and is off to India to be with family before starting his postdoctoral work. We will miss you Manoj! 

​

- July 2021 - 

​

Noah's paper on TRAPPIII was accepted to JMB, and Manoj and Kaelin's papers on PI3Ky were accepted into Structure and Science advances. Manoj was also a contributing author to "Accurate prediction of protein structures and interactions using a three-track neural network" published in Science. Great work everyone! 

​

Manoj has successfully defended his PhD thesis " Molecular basis for the regulation of phosphoinositide 3-kinase 𝛄 (PI3K𝛄)". Congrats! 

​

- May 2021 - 

​

Alex Shaw has joined the lab as a Co-op student. Welcome Alex!

​

Manoj gave a talk at the Kinases and Pseudokinases meeting (Biochem society) held virtually. Nice work Manoj! 

​

- April 2021 - 

​

Edward has successfully defended his MSc thesis “Carbohydrate Processing: An Indispensable Platform of Pneumococcal Virulence”. Congrats Ed! 

​

Manoj gave a talk at Experimental Biology (ASBMB). Great work Manoj!  

​

Kaelin is leaving the lab to complete her MSc in Public Health at the University of British Columbia. Good luck with your new career, you will be missed! 

​

- March 2021 - 

​

Manoj, Kaelin, Noah and Brandon's work on PI3Kγ was published in E.Life. Great work everyone! 

​

- December 2020 - 

​

Meredith and Noah's paper on TRAPPII was published in Communications Biology.

​

Brandon is leaving to study Nursing at the University of British Columbia Okanagan. Good luck Brandon, thanks for all of your help with the Mass Spec! 

​

- September 2020 - 

​

Matthew Parson has joined the lab as the new mass spec lab technician. Welcome Matt! 

​

Josephs directed studies work was published in the Journal of the American Society for Mass Spectrometry. He is now leaving to pursue a PhD at the MRC LMB in Dr Venki Ramakrishnan's lab. Good luck Joseph! 

​

- March 2020 - 

​

Jacob has successfully defended his PhD thesis “Molecular mechanisms of phosphatidylinositol 4-kinase III beta (PI4KB) regulation and their role in human disease”. Jacob has taken a position as a R&D Scientist at StressMarq Biosciences Inc. Good luck with the new job! 

​

- January 2020 - 

​

Harish has come from India and has joined the lab as PhD student. Welcome Harish!  

​

- December 2019 - 

​

Jacobs work on c10orf76 was published in EMBO reports. Great work! 

​

- November 2019 - 

​

Meredith has successfully defended her MSc thesis "Structural and Biochemical Investigation of the Regulation of Rab11a by the Guanine Nucleotide Exchange Factors SH3BP5 and TRAPPII”. Meredith is staying on as Lab Manager for the lab 

​

John was the recipient of the 2018-2019 University of Victoria Award for Research Excellence. 

​

- September 2019 - 

​

John was awarded a grant from the Cancer Research Society (CRS) to continue work on defining the molecular mechanism of activation of oncogenes in the Akt pathway. 

​

Brandon has joined the lab

​

- July 2019 - 

​

Jordan was accepted into Medical School at UBC. Congrats Jordan, we know you will do great things!

​

Reece is off to California for his PhD studies. Good luck Reece! 

​

- June 2019 - 

​

Gillian has successfully defended her PhD thesis "Defining the Molecular Mechanisms Mediating Class IA Phosphoinositide 3-kinase (PI3K) Regulation and their Role in Human Disease” and is off to Germany for her Postdoc. We will miss you!

​

- May 2019 - 

​

Gillian Dornan has received a Banting Postdoctoral Fellowship to continue her research in Germany at the Leibniz Institute for Molecular Pharmacology (FMP). Congrats Gill!

​

The HDX-MS conference John organized was held in Banff. Meredith gave a talk, while Jacob, Reece and Jordan all had posters. Great job everyone! 

​

- September 2018 - 

​

Meredith gave a talk at the FASEB SRC Small GTPase in Membrane Processes conference held in Leesburg, VA. 

​

- June 2018 - 

​

In recognition of his exceptional early career research on phosphoinositide kinases, John has received the Michael Smith Scholar Award.

​

- April 2018 - 

​

Meredith has been awarded a NSERC CGSM (Canada Graduate Scholarship- Masters) to continue her work on Rab11. Congrats!  

​

- February 2018 - 

​

Gillian, Jacob and Manoj are presenting their work at the Keystone Symposia on Phosphoinositide Biology: New Therapeutic Targets beyond Class I PI3K in New Mexico. 

​

- Oct 2017 -

​

Manoj, Meredith, and Braden's collaborative work with Daniel Gentile from Kevan Shokat's laboratory on the identification and characterisation of novel Ras inhibitors published in Cell Chemical Biology.

​

- Sept 2017 -

​

John has been awarded with the ASBMB Walter Shaw Young Investigator Award to be presented at the annual ASBMB meeting in San Diego. John can be seen receiving the award on the left. Also Meredith left her technician days behind to start graduate studies in the lab.

​

Jacob has been awarded an NSERC doctoral scholarship to continue his work on PI4K. Great work Jacob! 

​

- May 2017 -

​

Braden, Manoj and Meredith's paper on the activation of class IA PI3Ks by membrane localised HRas published in JBC. Coincides with Braden being accepted into medical school at the same time. Congrats all around!

​

- Feb 2017 -

​

Gillian, Braden, and Meredith's paper on immunodeficiency mutations in PIK3CD and PIK3R1 published today in PNAS. Congratulations to all!

​

- Jan 2017 -

​

Manoj Rathinaswarmy joins the lab as graduate student.

​

- Dec 2016 -

​

Jacob, Erik, and Merdith's paper on PI4K activation in viral infection was released in Structure.

​

- Sept 2016 -

​

The collaborative project examining malarial inhibitors from Dr. Stuart Schreiber's laboratory was just published in Nature. Congratulations to Jacob

and Gillian. The work was also written up in BBC news!

​

- May 2016 -

​

John just returned from giving a talk at the Phospholipase A2 meeting in La Jolla honouring his previous supervisor Ed Dennis. The photo to the left showcases all of the former Dennis lab trainees over the years.

 

- Feb 2016 -

​

Melissa and Jacob's paper in J Med Chem has been accepted. This collaboration with the Shokat lab at UCSF discusses our use of structure guided drug design to make new PI4KB inhibitors.

​

- Jan 2016 -

​

First last author paper from the group published in Protein Science. Also first paper published with the new mass spectrometer. Congratulations to Melissa, Jacob, and Meredith!

​

- Nov 2015-

​

PTEN HDX-MS paper published today in Biochemical Journal from John's postdoc.

Congratulations to Glenn!

​

- Oct 2015 -

​

First paper from the lab out today. A hopefully useful review on the use of HDX-MS to probe protein lipid assemblies. Also one of the last projects from John's postdoc published today in Science. The first experiments for this project were run in 2009!

​

- August 2015 -

​

The new mass spectrometer has arrived, time to get some H/D exchange experiments running.

 

- August 2015 -

​

Melissa is officially leaving us for medical school at UBC. We wish her the best of luck. Melissa was

the first researcher in the lab and has been an amazing asset in getting the lab equipped and the

first research projects up and running.

​

- July 2015 -

​

CIHR New investigator and CIHR open operating grant funded, a great sigh of relief by all in the lab.

​

- April 2014 -

​

The John Burke Lab is officially up and running at the University of Victoria